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LOCATION:Moscow\, Ordzhonikidze st.\, 3\, room 208
DESCRIPTION:A novel synthetic strategy based on 1\,3-dipolar cycloaddition of a-metalated isocyanides to double bond of different enamines and enaminones represent a direct\, simple and effective approach to 2\,4-substituted pyrroles from common and commercial available starting materials. We found that potassium tert-butoxide is a unique base which can be used for this type of cycloaddition. The new pyrroles were formed in good-to-excellent yields. 
DTSTART:20190917T151800Z
DTEND:20190917T171800Z
SUMMARY:Efimov Ilia «1\,3-Dipolar cycloaddition of -metalated isocyanides to enamines and enaminones: direct and convenient approach to 1H-2\,4-disubstituted pyrroles»
URL;VALUE=URI:/media/events/efimov-ilia-13-dipolar-cycloaddition-of--metalated-isocyanides-to-enamines-and-enaminones-direct-and-convenient-approach-to-1h-24-disubstituted-pyrroles/
DTSTAMP:20260506T070757Z
UID:69fabe9d8fbb4
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