Scientific seminar of post-doc Gaddam Krishna «First Total Synthesis of Furanocembranoid-1»
Scientific seminar of post-doc Gaddam Krishna «First Total Synthesis of Furanocembranoid-1»
2019 The event passed
15 Oct
Location
Moscow, Ordzhonikidze st., 3, room 102, Faculty of science
About the event
- Isolation and medicinal importance: In 2007, Khanitha Pudhom et al. isolated a class of furanocembranoids1 1 (Figure 1) from the hexane extract of croton oblengifolius roxb sp. Furanocembranoids-1 showed cytotoxicities againest BT474 (human breast ductol carcinoma), CHAGO (human undifferentiate lung carcinoma), Hep-G2 (human liver hepatoblastoma), KATO-3 (human gastric carcinoma) and SW-6 (human colon adrenocarcinoma).
- Retrosynthetic analysis: The presence of two stereogenic centers and a network of diverse and distributed functionalities on its novel framework and together with its potential bioactivity, make furanocembranoid-
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