RUDN scientists have created new substances to fight resistant bacteria
Biofilms are a bacterial “shield” that makes them almost invulnerable to drugs and immunity. Because of them, infections become chronic and difficult to treat. The new substances will help in the fight against such dangerous bacteria as E. Coli, Pseudomonas aeruginosa and Staphylococcus aureus.
“As a basis we took already known compounds - 5-aryl-2-aminoimidazoles. To them we added an amino group. This change allowed us to obtain compounds with improved ability to inhibit the formation of biofilms. We created a library of new derivatives with different substituents including halogens and alkyl chains. Their activity was tested on biological models and potential toxicity was assessed on human cell lines, immune cells and a nematode model (Caenorhabditis elegans),” - Erik Van der Eyken, Director of the Scientific Center for Microwave-assisted Organic Synthesis at RUDN.
The RUDN University Science and Innovation Prize winners were honoured at the extended meeting of the Academic Council. In 2024 the terms of the traditional RUDN University Prize were changed: for the first time the competition was announced in two categories: leading scientists and young scientists.
According to the International Energy Agency (IEA), electricity consumption in Africa has increased by more than 100% over the past two years (2020-2022). However, 74.9% of this energy is still produced by burning organic fuels — natural gas, coal and oil. At the same time, the level of electrification on the continent remains extremely low — only 24%, while in other developing countries it reaches 40%. Even in grid-connected areas, electricity supply is often unreliable: industrial enterprises lose energy on an average of 56 days a year.
Today, diagnosis and treatment planning with orthodontists takes several days. Also, complications can arise during treatment that slow down the patient's recovery process. For example, improper orthodontic treatment planning can lead to temporomandibular joint dysfunction.
The RUDN University Science and Innovation Prize winners were honoured at the extended meeting of the Academic Council. In 2024 the terms of the traditional RUDN University Prize were changed: for the first time the competition was announced in two categories: leading scientists and young scientists.
According to the International Energy Agency (IEA), electricity consumption in Africa has increased by more than 100% over the past two years (2020-2022). However, 74.9% of this energy is still produced by burning organic fuels — natural gas, coal and oil. At the same time, the level of electrification on the continent remains extremely low — only 24%, while in other developing countries it reaches 40%. Even in grid-connected areas, electricity supply is often unreliable: industrial enterprises lose energy on an average of 56 days a year.
Today, diagnosis and treatment planning with orthodontists takes several days. Also, complications can arise during treatment that slow down the patient's recovery process. For example, improper orthodontic treatment planning can lead to temporomandibular joint dysfunction.