Events and Invitations
Events
Seminar “On the solutions to initial boundary value problems for the Kawahara equation and its generalizations”
The report will consider model nonlinear equations of Sobolev type in the theory of waves in plasma and magnets. For relevant Cauchy problems obtained results on the existence of so-called critical exponents delimiting regions where there is no local solvability in time in the weak sense and where there is local solvability in time.
Seminar “Language aspects of integration and self-identification in the modern world”
The scientific seminar is dedicated to improving the quality of teaching foreign languages and cultures in accordance with the new challenges posed to humanitarian education; expanding active contacts with scientists and teachers of foreign languages and humanities from leading universities, raising the status of foreign languages and humanities, developing the academic reputation of the RUDN University and the incoming mobility of leading scientists.
Seminar “Quasi-classical (short-wave) asymptotics and the canonical Maslov operator”
The laboratory “Nonlinear and nonlocal problems of mathematical Physics and their applications” of RUDN together with MIAN conducts a series of mini-courses on modern analysis on the topic: “Quasi-classical (short-wave) asymptotics and the canonical Maslov operator”.
Seminar “N,O-Chelated azine-enol boron complexes featuring different fusion patterns of aromatic rings in the azine fragment”
In this study, a series of N,O-chelated azine-enol boron complexes featuring four different fusion patterns between the benzene and pyridine rings of the azine fragment was synthesized and characterized. The optical properties of the corresponding complexes have been assessed in dichloromethane solution and in solid state. In the latter case the assessment was performed for both powder samples as well as batches of single crystals allowing to identify several cases of mechanochromism and one case of polymorphism-dependent emission.
Seminar “Characterization of spatiotemporal dynamics in EEG data with optical flow patterns”
In this study, we investigate the spatiotemporal dynamics of the neural oscillations by analyzing the electric potential that arises from neural activity. To characterize these dynamics, we use optical flow patterns such as sources, sinks, spirals and saddles.
Seminar “Mathematical modeling of multiple myeloma intraclonal heterogeneity, drug resistance, and impact on erythropoiesis”
In this work, we will review some of our modeling studies devoted to MM heterogeneity, drug resistance, and impact on erythropoiesis. In this talk, we will introduce the biological background, clinical presentation, and treatment options for this disease.
Lecture “Metal Catalysis in Chemoselective Peptide Macrocyclization”
This lecture charts future perspective in the field, while bringing attention to the countless possibilities available by diversifying not only the metal, but also the reactivity modes and tactics to bring peptide functional groups together and produce structurally diverse macrocycles.
Lecture “Multicomponent Synthesis of Macrocyclic and Stapled Peptides”
This lecture highlights the development of a methodology that provides a repertoire of synthetic tools for the achievement of N-alkylated, macrocyclic peptides, including inhibitors of protein-protein interactions, antibacterial and anticancer peptides. The lecture also reports on the determination of the three-dimensional structures of the macrocyclic peptide serving a mimetics of protein secondary structures. This includes a detailed NMR study (i.e., TOCSY, COSY, HSQC HMBC, and ROESY) combined with molecular dynamic simulation.
Seminar “Absence of nontrivial weak solutions, some nonlinear algorithms with gradient nonlinearity”
Sufficient conditions for the absence of nontrivial weak solutions of nonlinear inequalities and systems with integer powers of the Laplace operator and with a nonlinear term of the form a(x)|∇(∆mu)|q+ b(x)|∇u|s are considered.
Seminar “Mathematical modeling of nonequilibrium phase transformations in metastable media”
The talk will consider issues related to modeling of nonequilibrium phase transformations in various physical systems rapidly reduced to a deep metastable state. Superheated liquid, supercooled melt, supersaturated solution will be considered as such systems.
Lecture “Multicomponent Reactions in the Development of Peptide Pharmaceuticals”
In this lecture, we describe novel all-on-resin strategies permitting the synthesis of super potent (nano- and picomolar) tubulysin and dolastatin analogs and their functionalization with cleavable linkers that allow their traceless release after the selective internalization into cancer cells. We also present synthetic methods towards novel targeting peptides and their conjugates to the cytotoxic payloads.