Cascade transformation brought a victory in a competition to RUDN chemists
The study "Dinitriles’ cascade transformations in basic medium" won the category "Chemistry, new materials and chemical technologies" of a contest of state support of young Russian PhD holders.
The research is aimed to create new domino reactions - effective methods for synthesis of organic compounds that might display useful properties.
RUDN scientists of the Faculty of Science conducted a series of studies of the properties of cyanomethyl thiazolium salts undergoing domino-reaction with salicylic aldehydes. Biological studies compounds obtained that way demonstrated their high cytotoxic activity. Detailed results offer hope for improving the effectiveness of some medications, including those against cancer.
"We pursue two main objectives in our studies - says the author - Aleksey Festa, PhD (Chemistry), Senior Lecturer at Organic Chemistry Department - Firstly, we want to create interesting and beautiful fundamental chemistry. Secondly, we are focused on the practical relevance which can manifest itself in the form of a biological activity or fluorescence properties of the compounds we obtain.
We hope to strengthen our cooperation with biologists, to make our hit-compounds candidates for medicine."
Creation of new types of domino processes inevitably attracts the attention of researchers from all over the world. Every year more than 500 studies are published in this research field.
Peoples’ Friendship University of Russia has strengthened its position in the QS Graduate Employability Rankings 2022. RUDN University is 126th in the world in “Employment of graduates”.
Preliminary results for 4 out of 11 subject rankings of THE World University Rankings by Subject 2022 have become known. RUDN University is represented in three of them: “Natural Sciences”, “Life Sciences” and “Medicine”.
Peoples’ Friendship University of Russia has risen to position 601-800 in the Times Higher Education World University Ranking 2022 (THE WUR 2022). The list includes only 1,662 universities in the world, 60+ of them are Russian.