Cascade transformation brought a victory in a competition to RUDN chemists

Cascade transformation brought a victory in a competition to RUDN chemists

The study "Dinitriles’ cascade transformations in basic medium" won the category "Chemistry, new materials and chemical technologies" of a contest of state support of young Russian PhD holders.

The research is aimed to create new domino reactions - effective methods for synthesis of organic compounds that might display useful properties.         

RUDN scientists of the Faculty of Science conducted a series of studies of the properties of cyanomethyl thiazolium salts undergoing domino-reaction with salicylic aldehydes. Biological studies compounds obtained that way demonstrated their high cytotoxic activity. Detailed results offer hope for improving the effectiveness of some medications, including those against cancer.

"We pursue two main objectives in our studies - says the author - Aleksey Festa, PhD (Chemistry), Senior Lecturer at Organic Chemistry Department - Firstly, we want to create interesting and beautiful fundamental chemistry. Secondly, we are focused on the practical relevance which can manifest itself in the form of a biological activity or fluorescence properties of the compounds we obtain.

We hope to strengthen our cooperation with biologists, to make our hit-compounds candidates for medicine."

Creation of new types of domino processes inevitably attracts the attention of researchers from all over the world. Every year more than 500 studies are published in this research field.

News
All news
About RUDN
16 Jun
RUDN University becomes the best Russian university in the ARWU subject ranking in "Agriculture" and goes 100 positions up in "Mathematics"

Peoples’ Friendship University of Russia has become the best among Russian universities in the international ARWU (Shanghai Ranking’s Global Ranking of Academic Subjects) ranking in Agriculture. RUDN University entered this ranking for the first time and immediately found itself among 201-300 best. The university also shot up 100 positions in Mathematics.

About RUDN
09 Jun
RUDN University — # 317 in the ranking of the best universities in the world QS WUR 2022

According to the ranking of the best universities in the world QS World University Rankings 2022, RUDN University has risen by 9 positions and took the 317th place.

About RUDN
23 Apr
RUDN University in the Times Higher Education Impact Ranking 2021

THE University Impact Rankings analyzes the impact of higher education on the development of society and the achievement of the UN Sustainable Development Goals.