3
RUDN University Chemists obtained coenzyme from Parsley and Dill seeds

RUDN University Chemists obtained coenzyme from Parsley and Dill seeds

Scientists from RUDN University have developed a new method for converting planthydrocarbon radicals into substances that canbe used to synthesize coenzyme Q0.

Coenzymes of the Q group in mammals and plants are responsible for maintaining the energy metabolism of cells. They are powerful antioxidants and regulate the permeability ofmitochondrial membranes. Coenzyme Q0 is known to reduce and even suppress metastasis in breast, skin and ovarian cancers.

“We proposed a simple way to obtain the necessary element for the synthesis of Q0 precursors based on allylpolymethoxybenzenes. It is easy to isolate them in large quantities from parsley and dill extract,” says RUDN scientist Viktor Khrustalev.

The main stage on the way of obtaining a coenzyme is hydrogenation to allylpolymethoxybenzenes fragments. This process takes place in a special apparatus with a fluoroplastic insert using aporous palladium catalyst. After use, the reaction mixture is separated from the catalyst without additional filters.

The minimum reaction time is 4 to 8 hours. However, with an increased hydrogen pressure,the reaction takes 2-4 hours. Even with accelerated production, no methylbenzene by-products remain after hydrogenation, which simplifies further purification. The catalyst canthen be used up to 40 times.

"With the help of X-ray diffraction analysis, we have confirmed the spatial structure of there sulting compound. This allows further study of its antitumor and antioxidant properties,"explained Viktor Khrustalev, Doctor of Chemistry, Head of the Department of Inorganic Chemistry of the Peoples’ Friendship University of Russia.

Mendeleev Comunications 

Scientific Conferences View all
16 Oct
The collection consists of two volumes and includes biographical information about Russian demographers and their scientific research. The first volume is devoted to the research of the Pre-Revolutionary period, the second to the works of the Soviet era and the present.
100
30 Jan 2018
The conference on international arbitration, where law students from European universities simulate court proceedings and alternately defend the interests of the respondent and the orator.
1300
Similar newsletter View all
16 Oct
Green Diplomacy Center opened in RUDN

A Center for Green Diplomacy was created based on the RUDN Institute of Environmental Engineering. Among the goals is the integration of the results of scientific and practical activities into the development of international relations in the environmental sphere. The center's specialists will also accompany the corporate sector in solving various environmental problems.

108
19 Apr
A huge pizza and a jug of water, why should 5G networks be sliced? The winners of RUDN science competition explain

RUDN summarized the results of the scientific competition "Project Start: work of the science club ". Students of the Faculty of Physics, Mathematics and Natural Sciences have created a project for a managed queuing system using a neural network to redistribute resources between 5G segments. How to increase flexibility, make the network fast and inexpensive and reach more users — tell Gebrial Ibram Esam Zekri ("Fundamental Computer Science and Information Technology", Master's degree, II course) and Ksenia Leontieva ("Applied Mathematics and Computer Science", Master's degree, I course).

175
19 Apr
Lyricists and physicists are now on equal terms: the first humanitarian laboratory opened in RUDN

What is your first association with the word “laboratory”? Flasks and beakers? Microscopes and centrifuges? Yes, many of us would answer the same way.

221
Similar newsletter View all