Fluorescent optical DNA biosensor

The invention pertains to biotechnology, more specifically to optical biosensors designed for determination of protein molecules in small concentrations. The fluorescent optical DNA biosensor has the ability to repeated usage without loss of sensitivity, more specifically when determining protein molecules at low concentrations.

L.A.Butusov I.A.Nagovitsyn V.V.Kurilkin G.K.Chudinova

Medicine Medical Biotechnology

№2616879 Registered 18 Apr 2017

  • Priority04 Mar 2016
  • Class of ICPIG01
  • Application number2016107983
  • PublicationRospatent Bul. No. 11

Method for preparing earthworms for studying the infection they get by helminthic eggs

The invention pertains to biology, microbiology, more specifically to parasitology, and can be used for fundamental research on the possibility of interaction of test substances, biological objects, and other tested substances with the body of earthworms (Lumbricina).

V.V.Erofeeva A.V.Khrustalev V.P.Pukhlyanko

Medicine Medical Biotechnology

№2578511 Registered 25 Feb 2016

  • Priority12 Mar 2015
  • Class of ICPIG01
  • Application number 2015108635
  • PublicationRospatent Bul. No. 9

Method for extracting a mixture of DNA and proteins from Trypanosoma cruzi epimastigotic forms

The invention pertains to biotechnology, more specifically to a method for extracting a mixture of DNA and proteins from the epimastigotic forms of the strain TPAP / MX / 2002 / Albarrada culture of Trypanosoma cruzi. The described method includes the production of a biomass of a culture of the strain. The invention makes it possible to obtain a product with a reduced content of protein components.

L.P.Karpenko V.G.Melnikov E.G.Kravtsov M.V.Dalin R.R.Sadretdinova A.V.Zhigunova N.V.Yashina

Medicine Medical Biotechnology

№2558235 Registered 01 Jul 2015

  • Priority27 Sep 2013
  • Class of ICPIC12
  • Application number 2013143683
  • PublicationRospatent Bul. No. 21

Wound healing agent based on Trichoderma harzianum Rifai strain

The invention pertains to the field of biochemistry and pertains to the use of a concentrate of culture liquid of the Trichoderma harzianum Rifai strain, deposited in the All-Russian Collection of Industrial Microorganisms under No. F-180, as a wound-healing agent in case of skin damage. The invention is directed to the expansion of the arsenal of means providing healing of skin wound lesions.

I.P.Smirnova O.A.Semkina L.M.Kishmakhova

Medicine Medical Biotechnology

№2528065 Registered 10 Sep 2014

  • Priority10 Apr 2013
  • Class of ICPIA61
  • Application number2013116206
  • PublicationRospatent Bul. No. 25

Inhibitor of the causative agent of a bacterial burn of fruit crops (Erwinia Amylovora)

The invention pertains to biotechnology and can be used in crop production. The strain of the fungus Trichoderma harzianum Rifai VKPM F-180 is used as a producer of an inhibitor of the causative agent of a bacterial burn of fruit crops. The invention reduces the loss of ornamental and fruit crops caused by the bacterium Erwinia amylovora. Trichoderma harzianum Rifai strain is used as an inhibitor of the causative agent of a bacterial burn of fruit crops.

E.V.Karimova Yu.A.Shneyder I.P.Smirnova

Medicine Medical Biotechnology

№2493247 Registered 20 Sep 2013

  • Priority15 May 2012
  • Class of ICPIC12
  • Application number2012109980
  • PublicationRospatent Bul. No. 26

Inhibitor of tick-borne encephalitis virus

The invention pertains to the field of virology and biotechnology and can be used in medicine. To inhibit tick-borne encephalitis virus, the L-lysine-α-oxidase produced by Trichoderma harzianum Rifai strain VKPM F-180 is used. The invention makes it possible to suppress the viral activity of tick-borne encephalitis in cells in vitro. 2 tab.

I.P.Smirnova V.F.Larichev

Medicine Medical Biotechnology

№2473689 Registered 27 Jan 2013

  • Priority08 Sep 2011
  • Class of ICPIC12
  • Application number201113701
  • PublicationRospatent Bul. No. 3