Seminar “Reticular network as the Lymph Nodes railroad system: T-cells migration modeling by the free energy minimization technique”
One of the most important structural and functional elements of lymph nodes (LN) is the fibroblasts reticular network. Placed in vivo in the LN space, lymphocytes can move directionally, in fact, just along the reticular network, which act as a central immune highway. However, despite the multiple experimental studies, mechanisms regulating the lymphocytes motion are not fully understood.