Efimov Ilia «1,3-Dipolar cycloaddition of -metalated isocyanides to enamines and enaminones: direct and convenient approach to 1H-2,4-disubstituted pyrroles»
Efimov Ilia «1,3-Dipolar cycloaddition of -metalated isocyanides to enamines and enaminones: direct and convenient approach to 1H-2,4-disubstituted pyrroles»
The event passed
17 Sep 2019
Location
Moscow, Ordzhonikidze st., 3, room 208
About the event
A novel synthetic strategy based on 1,3-dipolar cycloaddition of a-metalated isocyanides to double bond of different enamines and enaminones represent a direct, simple and effective approach to 2,4-substituted pyrroles from common and commercial available starting materials. We found that potassium tert-butoxide is a unique base which can be used for this type of cycloaddition. The new pyrroles were formed in good-to-excellent yields.
Related eventsAll events
Energy and electronic effects in control of organic reactions From stereoelectronic frustration to electron upconversion
Direction:
Chemistry
Format:
Lecture
Organizer:
Research Institute of Chemistry
Type:
Inter-university