Seminar on mathematical modeling in biology and medicine on topic “Modeling the features of blood flow in portal hypertension”
Speaker: Mukhin Sergey, Professor of Lomonosov Moscow State University
Topic: Modeling the features of blood flow in portal hypertension
Many liver diseases are accompanied by venous flow obstruction and an increase of pressure in the portal vein. It leads to the development of dangerous complications. We investigate principal features of redistribution of blood flow in such disease with methods of mathematical modeling. The quasi-one-dimensional model of blood flow in the enclosed blood
circulations system with a detailed network of liver blood vessels is considered. The results of numerical experiments of investigation of blood flow in the normal case and under different degrees of loss of functional volume of liver parenchyma with consideration of mutual influence on flow from other organs and in typical surgical interventions are shown.