Annotations

Clinical and morphological evaluation of the effect of medicinal forms of carprofen on the gastrointestinal tract of small animals

Authors

Anna Savochkina

Country

Russia

Year of defence

2017

Scientific guidance

Arfenya Karamyan

Annotation to the dissertation: Among the diseases of small animals acutely there is a problem of safe relief of pain of various Genesis, and also a question post-operative analgesia. In this regard, frequency and wide range of applications nonsteroidal anti-inflammatory drugs (NSAIDs) in veterinary medicine are determined by the irreplaceability of this group of drugs in therapy diseases accompanied by inflammation and severe pain Drugs of this group have a specific negative impact on the metabolism of the mucosa the digestive tract, reducing its protective potential and resistance to damaging aggressive effects of Exo-and endogenous factors. Greatest characteristic manifestation of systemic adverse effects of these drugs on digestive organs is gastroenteropathy-pathology, characterized by the appearance of hemorrhagic inflammation of the mucosa, bleeding and erosion, as well as taking drugs of this group has negative effect on the functioning of the liver, kidneys and cardiovascular system.