2
The history of the "Perftoran" must be continued

The history of the "Perftoran" must be continued

At the end of the last century, Soviet scientists proposed the drug “Perftoran” as a blood substitute, which today could safely be called innovative. Created on the basis of perfluorocarbon compounds, it could compensate for the lack of oxygen in the patient’s body due to the absorption mechanism of its transfer. However, the composition, unofficially named for the color “blue blood”, revealed certain shortcomings, which the authors were not able to eliminate at the time. We could not do it abroad.

Employees of the center for collective use (Scientific and educational center) of the Russian Academy of Sciences took up this difficult task. The reason for this was the developing COVID-19 pandemic in the world.

It is known that oxygen deficiency affects the severity of ischemic brain and heart damage, shock and collapse states, infectious and non-infectious diseases, the formation of multiple organ failure and stressful situations.

The research team led by the Director of the center for biotechnology and synthesis of Common Use Center (Research and Educational Center) of RUDN University Arkady Khromov formed a new algorithm for obtaining perfluorocarbon blood substitutes with nanoscale emulsion particles, which will ensure its low viscosity and oxygen delivery to the final link of the systemic blood flow — the capillary. The developers also know how to make the infusion drug stable during its long-term storage without freezing.

To implement the project, funding is required. To date, an application for a grant from the Russian Foundation for basic research (RFBR) on the topic “Fundamental research on the development of drugs based on perfluorocarbon compounds for the delivery of oxygen to the body tissues of a patient infected with coronavirus” has been issued.

We wish our colleagues good luck in achieving this goal.

Scientific Conferences View all
12 Dec 2024
About 200 participants from Russia and 20 countries met at the National Interdisciplinary Scientific Seminar with International Participation “Law in Medicine. Medicine in Law: Points of Contact”. The subject was “Happy Motherhood: unsolved problems of obstetrics, gynaecology and perinatology”.
596
Visiting Professors View all
12 Dec 2024
In 2024, RUDN started accepting applications for the new annual Prize for Scientific Achievement in Chemistry. The award was established to honour contributions to fundamental and applied research, as well as merit in achieving the UN Sustainable Development Goals.
826
Similar newsletter View all
28 Nov
To chip the placenta. RUDN University researcher wins a competition for young scientists with a cell model

The project to develop a cellular model of the placenta became the winner in the Scientific Materials category of the Young Scientists 3.0 competition, organized with the support of the Presidential Grants Foundation and T-Bank.

16
28 Nov
The White List: 10 scientific journals from RUDN University have been included in the first highest level of the state list of scientific publications

Ten scientific journals published by RUDN University have been included in the highest level of the state list of scientific publications, the White List.

17
28 Nov
The role of fungi in maintaining tree diversity has been unraveled – a global study involving scientists from RUDN University

Forests are not only the lungs of the planet, but also home to millions of species. However, it has remained unclear how underground interactions between trees and fungi affect forest species richness in different climatic conditions. Previous studies have yielded conflicting results: in some regions, the dominance of certain fungi reduced tree diversity, while in others it increased it.

16
Similar newsletter View all