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The history of the "Perftoran" must be continued

The history of the "Perftoran" must be continued

At the end of the last century, Soviet scientists proposed the drug “Perftoran” as a blood substitute, which today could safely be called innovative. Created on the basis of perfluorocarbon compounds, it could compensate for the lack of oxygen in the patient’s body due to the absorption mechanism of its transfer. However, the composition, unofficially named for the color “blue blood”, revealed certain shortcomings, which the authors were not able to eliminate at the time. We could not do it abroad.

Employees of the center for collective use (Scientific and educational center) of the Russian Academy of Sciences took up this difficult task. The reason for this was the developing COVID-19 pandemic in the world.

It is known that oxygen deficiency affects the severity of ischemic brain and heart damage, shock and collapse states, infectious and non-infectious diseases, the formation of multiple organ failure and stressful situations.

The research team led by the Director of the center for biotechnology and synthesis of Common Use Center (Research and Educational Center) of RUDN University Arkady Khromov formed a new algorithm for obtaining perfluorocarbon blood substitutes with nanoscale emulsion particles, which will ensure its low viscosity and oxygen delivery to the final link of the systemic blood flow — the capillary. The developers also know how to make the infusion drug stable during its long-term storage without freezing.

To implement the project, funding is required. To date, an application for a grant from the Russian Foundation for basic research (RFBR) on the topic “Fundamental research on the development of drugs based on perfluorocarbon compounds for the delivery of oxygen to the body tissues of a patient infected with coronavirus” has been issued.

We wish our colleagues good luck in achieving this goal.

Scientific Conferences View all
03 Nov 2017
RUDN University organized the first 5G Summit R&D Russia on June 19 - 20, 2017
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Student's Scientific Initiatives View all
03 Nov 2017
June 22 - 26, 2017 in Barnaul, Altai State University, took place the Summer Academy of the BRICS Youth Assembly, an international event that brought together representatives of different countries
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30 Dec
Biologists from RUDN University discovered the secret of flaxseed oil with long shelf life

Biologists from RUDN University working together with their colleagues from the Institute of Molecular Biology of the Russian Academy of Sciences and the Institute of Flax studied the genes that determine the fatty acid composition in flaxseed oil and identified polymorphisms in six of them. The team also found out what gene variations could extend the shelf life of flaxseed oil. This data can be used to improve the genetic selection of new flax breeds. The results were published in the BMC Plant Biology journal.

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11 Oct
Mowing Is More Harmful to Soil Than Grazing

A team of biologists analyzed soil samples from a pasture and a regularly mowed meadow and found out that grazing lets more carbon get into the soil than mowing. This, in turn, improves the carbon cycle and makes microorganisms more efficient.

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11 Oct
Soil scientists suggest method for remediating urban garden soils contaminated with lead and arsenic

The soils of urban gardens and vegetable patches contain a lot of toxicants (including lead and arsenic) in high concentrations which can be harmful to the health of children and people with chronic diseases. A team of soil scientists from RUDN University suggested a remediation method developed based on data collected in a garden of Brooklyn (NY, U.S.).

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