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The history of the "Perftoran" must be continued

The history of the "Perftoran" must be continued

At the end of the last century, Soviet scientists proposed the drug “Perftoran” as a blood substitute, which today could safely be called innovative. Created on the basis of perfluorocarbon compounds, it could compensate for the lack of oxygen in the patient’s body due to the absorption mechanism of its transfer. However, the composition, unofficially named for the color “blue blood”, revealed certain shortcomings, which the authors were not able to eliminate at the time. We could not do it abroad.

Employees of the center for collective use (Scientific and educational center) of the Russian Academy of Sciences took up this difficult task. The reason for this was the developing COVID-19 pandemic in the world.

It is known that oxygen deficiency affects the severity of ischemic brain and heart damage, shock and collapse states, infectious and non-infectious diseases, the formation of multiple organ failure and stressful situations.

The research team led by the Director of the center for biotechnology and synthesis of Common Use Center (Research and Educational Center) of RUDN University Arkady Khromov formed a new algorithm for obtaining perfluorocarbon blood substitutes with nanoscale emulsion particles, which will ensure its low viscosity and oxygen delivery to the final link of the systemic blood flow — the capillary. The developers also know how to make the infusion drug stable during its long-term storage without freezing.

To implement the project, funding is required. To date, an application for a grant from the Russian Foundation for basic research (RFBR) on the topic “Fundamental research on the development of drugs based on perfluorocarbon compounds for the delivery of oxygen to the body tissues of a patient infected with coronavirus” has been issued.

We wish our colleagues good luck in achieving this goal.

Main Publications View all
15 Nov 2017
RUDN University scientists publish results of their scientific researches in highly-recognized in whole world and indexed in international databases journals (Web of Science, Scopus ect.). That, of course, corresponds to the high status of the University and its international recognition. Publications of June-September 2017 ( In Journals of categories Q1-Q3)
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Visiting Professors View all
03 Nov 2017
Michele Pagano is a graduate of the University of Pisa, a leading scientist, the author of more than 200 publications in international journals, and a participant in many international research projects
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RUDN University mathematician determined the conditions for the coexistence of three species in the wild

RUDN University mathematician together with colleagues from India and France for the first time studied in detail the system of coexistence of three species of living creatures in the wild. The results help to understand what parameters determine the extinction andли survivalof species, and how the number of species changes in space and time.

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21 Oct
RUDN University Chemist Created Coordination Polymers Films with up to 99.99% antibacterial efficiency

RUDN University chemist with his colleagues from Portugal has developed two types of coating based on new coordination polymers with silver. Both compounds were successfully tested against four common pathogens.

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