3
RUDN University biologist found that Chinese date improves the immune system of fish

RUDN University biologist found that Chinese date improves the immune system of fish

RUDN University biologist proved that the extract of the fruit of the Chinese date boosts immunity in carp. The addition of date juice to the diet increases the reaction of the immune system of fish to extraneous compounds.

In fisheries, antibiotics are usually used to prevent infections. However, their use leads to the emergence of strains of bacteria resistant to them. This is a potential threat not only to fish but also to humans — in case that antibiotic-resistant bacteria begin to be transmitted from person to person. Researchers are looking for alternative drugs suitable for use in ichthyology.

Morteza Yousefi, a biologist from the RUDN University, and his colleagues investigated the properties of Zizyphus (Zizyphus jujube), known as “Chinese date” and found that it can be used as an antimicrobial agent for fish.

Morteza Yousefi tested the immunostimulatory properties of this plant on carp (Cyprinus carpio). The biologists gave the fish a solution of ethanol and distilled water with Ziziphus fruit juice with a concentration of 0.25%, 0.5%, and 1%. Then they took samples from the fish mucosa and monitored how immune parameters change: the number of antibodies, the activity of enzymes — proteases and the expression of genes of signaling molecules — cytokines, which, in particular, trigger phagocytosis, that is, the destruction of bacteria.

Analysis of the data showed that carp, which were given a solution of the fetus with a concentration of 0.5%, increased the number of antibodies. The more antibodies in the blood, the more extraneous compounds — antigens — they can “catch”.

Besides, ichthyologists have found a connection between the extract of dates in the diet of fish and the presence of cytokines. The experiment showed that the concentration of the solution is 0.25% does not change the immune reactions of carp, but 0.5% and 1% solution increases the expression of cytokine genes and the activity of protease enzymes that are involved in the “digestion” of killed pathogenic bacteria and in triggering the processes of extraneous cells death (apoptosis).

The experiment showed that the juice of the Chinese date can increase the immunity of carp, which means that it can be used as an antibacterial agent in fisheries working on the principle of “green aquaculture”. The discovery of immune stimulation of the carp juice of Ziziphus fruit in the future will allow fishermen to reduce the damage from infections, without provoking the emergence of antibiotic-resistant strains of bacteria.

The results are published in the journal Fish and Shellfish Immunology.

International scientific cooperation View all
03 Nov 2017
The main goal of the RUDN University and UNISDR Office for Northeast Asia and Global Education and Training Institute for Disaster Risk Reduction at Incheon (UNISDR ONEA-GETI) cooperation is to obtain knowledge about disaster risk reduction and international experience in this area for creating training courses for basic and additional professional education in RUDN
1390
Student's Scientific Initiatives View all
03 Nov 2017
June 22 - 26, 2017 in Barnaul, Altai State University, took place the Summer Academy of the BRICS Youth Assembly, an international event that brought together representatives of different countries
1441
Similar newsletter View all
07 Jul
RUDN University Biologist: salted water saves fish from stress when transporting

RUDN University biologist with colleagues from Brazil and Iran found how to alleviate the stress of fish during transportation. It turned out that this can be achieved with salted water.

62
20 Apr
RUDN University agronomists increased wheat yield by 65%

RUDN University agronomists have proposed a new scheme for fertilizing winter wheat, which allows increasing the yield by 68%. The key to this is in the combination of nitrogen and growth regulators.

123
20 Apr
RUDN Biologists Study Live Microorganisms in Toxic Liquids for Metalworking

RUDN biologists have studied microorganisms that can survive in metalworking fluids. The results will allow “picking up” bacteria and fungi that can process toxic waste fluids into a harmless product.

117
Similar newsletter View all