Nobel Prize in Medicine awarded for receptor research
“Tactile and temperature receptors are very important. Without them, a rare organism would have survived in extreme environmental conditions. They are present not only in humans, but also in many animals, even invertebrates. Being in the skin of the entire surface of the body and even in the mucous membranes, for example, in the oral cavity, they allow the body to avoid excessively hot, cold and other irritants”, said Igor Kastyro, Ph.D., Senior Lecturer at the Department of Normal Physiology, RUDN University.
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RUDN University scientists are also researching receptors. At the Department of Normal Physiology of RUDN Medical Institute, doctors invented a device with which it is possible to determine the body’s sensitivity to heat.
“Heat receptors can also act as pain receptors, since extreme temperatures are perceived by the body as pain. At the Department of Normal Physiology, RUDN University, we have proposed a new version of the thermoesthesiometer — a device for studying temperature sensitivity. It is used to determine the limits of human sensitivity to temperature,” said Igor Kastyro.
The research of RUDN University scientists will help to more accurately determine how acclimatization takes place in conditions far from the usual climate and adaptation to new weather conditions.
“Many foreigners from warm countries study at RUDN University. Arriving in Russia, they find themselves in conditions of a long period of low temperatures. We want to observe how the number of these receptors in them changes over time, how their body adapts to low temperatures,” noted Igor Kastyro.
RUDN University physicians have identified genetic characteristics that may affect the predisposition to re-stenosis — narrowing of the lumen of the vessel — after the installation of a stent. The results will help to determine the risk of restenosis and select personalized therapy more accurately.
RUDN chemists have created a reusable catalyst for the oxidation of sulfides for the synthesis of drugs, dyes, and other compounds. It can “switch” the final product and provides “green” reaction conditions.
RUDN University and Shahid Beheshti University (SBU) chemist together with colleagues from Iran created a hydrogel film for wound dressing. It protects the wound from germs and is harmless to healthy tissues. Moreover, its porous structure can hold antibiotic, which kills dangerous microorganisms and provide additional protection.
RUDN University physicians have identified genetic characteristics that may affect the predisposition to re-stenosis — narrowing of the lumen of the vessel — after the installation of a stent. The results will help to determine the risk of restenosis and select personalized therapy more accurately.
RUDN chemists have created a reusable catalyst for the oxidation of sulfides for the synthesis of drugs, dyes, and other compounds. It can “switch” the final product and provides “green” reaction conditions.
RUDN University and Shahid Beheshti University (SBU) chemist together with colleagues from Iran created a hydrogel film for wound dressing. It protects the wound from germs and is harmless to healthy tissues. Moreover, its porous structure can hold antibiotic, which kills dangerous microorganisms and provide additional protection.