What is translational medicine? 5 interesting facts

What is translational medicine? 5 interesting facts

Translational medicine is an interdisciplinary branch of the biomedical field. It combines elements of clinical medicine and biotechnological approaches to the development of new therapeutic and diagnostic agents. Translational medicine is designed to create optimal mechanisms for implementing the most significant achievements of fundamental science into clinical practice. It is necessary for the rapid resolution of urgent problems in medicine, saving the lives and health of patients who do not have full access to effective care today.

Research in this area usually takes place in 3 stages:

  • Clinical research, that is, the translation of scientific discoveries into practice in specific settings.
  • Assessment of how feasible it is to use new developments in real life, i.e., with the participation of patients.
  • implementation of the results into the practice of the current health care system.

5 interesting facts about translational medicine and its branches.

  • The term “translational oncology” first appeared in the scientific literature about 15 years ago, although the field has a longer history.
  • The concept of translational research emerged from the US National Cancer Institute at the 1992 National Conference on Cancer Prevention and Early Detection. Where James L. Mulshine and colleagues discussed how epithelial cancers could be blocked in the early stages of tumorigenesis if agents were developed to interfere with growth factors or other molecules involved in tumor promotion:
  • By combining basic research in tumor cell biology with technological advances in immune cell engineering, therapeutic antibodies and vaccines against cancer can be developed. The vaccine will deliver tumor antigen to prime and activate tumor-specific immunity.
  • Immunotherapy is one of the areas of translational oncology. Science hailed cancer immunotherapy as its breakthrough of the year, echoed by the American Society of Clinical Oncology in 2016.
  • The use of translational research has spread beyond oncology to medicine in general, and then to non- clinical fields such as engineering. This was made possible by the combination of basic research and clinical practice in translational medicine.

In 2021, a special “Translational Medicine” cluster was created at RUDN. It is aimed at conducting scientific, registration preclinical, and clinical research.

30 Jan 2018
The conference on international arbitration, where law students from European universities simulate court proceedings and alternately defend the interests of the respondent and the orator.
Research and Innovative Activity View all
30 Dec 2020
In 2017, RUDN University scientists constructed a new explicit second-order precision difference scheme using modern computer algebra methods for 2-dimensional Navier-Stokes equations (NSE) [1]. This year, our mathematicians used a new scheme [2] to construct a numerical solution to the Cauchy problem with initial data (for t=0) as satisfying the continuity equation. Scientists managed to achieve previously unattainable accuracy of the continuity equation.
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31 Mar
RUDN scientists Samvel Apresyan and Alexander Stepanov were awarded Rospatent’s Gold Medal of honor "For the Good of Russia".

On January 21, 2021, the ceremony of awarding was held in the The Moscow Digital Business Space

31 Mar
The Day of Russian Science in RUDN

Being a scientist means creating a better future for the country and the world! RUDN scientists set ambitious goals for themselves, conduct advanced scientific research, make discoveries and bring Russian technologies to foreign markets. They have at their disposal more than 200 laboratories with modern high—tech equipment. Every year, RUDN holds more than 150 international scientific events, and university scientists patent about 100 new developments. Advances in research — from new cancer treatments to “cleaning up” space debris — are designed to improve human life.

31 Mar
RUDN researchers have prepared for publication a special issue ‘THE FUTURE OF MATHEMATICAL COSMOLOGY’ of the world’s oldest scientific journal Philosophical Transactions of the Royal Society (Proceedings of the British Academy of Sciences)

At the suggestion of the Royal Society, for the first time in history, scientists of a Russian university — from the Institute of Gravitation and Cosmology of RUDN, Professors Spiros Cotsakis (Greece) and Alexander P. Yefremov (Russia) — were invited as responsible editors and authors of a special thematic issue “The Future of Mathematical Cosmology” of the scientific journal Philosophical Transactions (series A, quartile Q1).

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