What is translational medicine? 5 interesting facts

What is translational medicine? 5 interesting facts

Translational medicine is an interdisciplinary branch of the biomedical field. It combines elements of clinical medicine and biotechnological approaches to the development of new therapeutic and diagnostic agents. Translational medicine is designed to create optimal mechanisms for implementing the most significant achievements of fundamental science into clinical practice. It is necessary for the rapid resolution of urgent problems in medicine, saving the lives and health of patients who do not have full access to effective care today.

Research in this area usually takes place in 3 stages:

  • Clinical research, that is, the translation of scientific discoveries into practice in specific settings.
  • Assessment of how feasible it is to use new developments in real life, i.e., with the participation of patients.
  • implementation of the results into the practice of the current health care system.

5 interesting facts about translational medicine and its branches.

  • The term “translational oncology” first appeared in the scientific literature about 15 years ago, although the field has a longer history.
  • The concept of translational research emerged from the US National Cancer Institute at the 1992 National Conference on Cancer Prevention and Early Detection. Where James L. Mulshine and colleagues discussed how epithelial cancers could be blocked in the early stages of tumorigenesis if agents were developed to interfere with growth factors or other molecules involved in tumor promotion:
  • By combining basic research in tumor cell biology with technological advances in immune cell engineering, therapeutic antibodies and vaccines against cancer can be developed. The vaccine will deliver tumor antigen to prime and activate tumor-specific immunity.
  • Immunotherapy is one of the areas of translational oncology. Science hailed cancer immunotherapy as its breakthrough of the year, echoed by the American Society of Clinical Oncology in 2016.
  • The use of translational research has spread beyond oncology to medicine in general, and then to non- clinical fields such as engineering. This was made possible by the combination of basic research and clinical practice in translational medicine.

In 2021, a special “Translational Medicine” cluster was created at RUDN. It is aimed at conducting scientific, registration preclinical, and clinical research.

Scientific Conferences View all
03 Nov 2017
RUDN University organized the first 5G Summit R&D Russia on June 19 - 20, 2017
Research and Innovative Activity View all
30 Dec 2020
In 2017, RUDN University scientists constructed a new explicit second-order precision difference scheme using modern computer algebra methods for 2-dimensional Navier-Stokes equations (NSE) [1]. This year, our mathematicians used a new scheme [2] to construct a numerical solution to the Cauchy problem with initial data (for t=0) as satisfying the continuity equation. Scientists managed to achieve previously unattainable accuracy of the continuity equation.
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07 Jul
RUDN University professor spoke at a workshop on mathematical modeling in biology and medicine in Italy

The city of Arpino (Italy) hosted an international workshop on mathematical modeling in biology and medicine. Reports were presented by 59 leading experts from 7 countries. Professor Volpert, Director of the Interdisciplinary Scientific Center for Mathematical Modeling in Biomedicine, spoke on behalf of RUDN.

07 Jul
RUDN University team have won The Gold medal at the International Archimedes Salon of Inventions and Innovative Technologies

Scientists from Institute of Digital Dentistry of the RUDN Institute of Medicine. presented their engineering design at the International Archimedes Salon of Inventions and Innovative Technologies

20 Apr
About remote sensing of the earth — RUDN University ecologists at a conference in Egypt

In December, associate professors of the RUDN Institute of Ecology spoke at a conference on remote sensing and space sciences in Egypt, which brought together 150 scientists from 8 countries: Egypt, Turkey, Italy, the USA, India, Iraq, Saudi Arabia, Russia.

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