The legacy of Academician Paltsev: RUDN University hosted the first conference on the functional morphology of the tissue microenvironment

At the opening, First Vice-Rector and Vice-Rector for Research at RUDN Andrey Kostin noted the key role of Academician Paltsev’s scientific school and the relevance of integrating morphological research into modern healthcare. Professor of the Russian Academy of Sciences Ekaterina Paltseva spoke about the scientist’s outstanding contribution to the creation of molecular medicine.

Fundamental research as the basis for the medicine of the future

The conference focused on advanced methods for studying living tissues: multiplex histology, digital spatial profiling, research into mitochondrial biology and the ultrastructure of the extracellular matrix. The presentations clearly demonstrated how the integration of cellular, molecular and tissue approaches is revealing new patterns in the understanding of oncogenesis, fibrosis, ageing and resistance mechanisms.

In his presentation, Dmitry Atyakshin, Director of the Research Centre for Innovative Immunophenotyping Technologies at RUDN University, Doctor of Medical Sciences, revealed the potential of multiplex histological methods in analysing the tissue microenvironment and solving key problems in functional morphology.

“Multiplex histological approaches have great potential for discovering new patterns in the organisation of biological tissues. The knowledge helps in the development of innovative drugs and treatment protocols for a wide range of pathologies,” Dmitry Atyakshin emphasised.

The centre’s leading researcher Irina Chekmareva, presented a study on the key role of specific cells, telocytes, in intercellular communication.

“Many serious diseases are associated with disturbances in cell communication networks. Studying the role of telocytes and developing ways to correct disturbances in intercellular information exchange are important for understanding the pathogenesis of diseases and discovering new therapeutic targets. Promising therapeutic approaches aimed at normalising the functioning of telocytes have been developed, which promises to improve the treatment outcomes for many pathologies,” Irina Chekmareva noted.

International cooperation and new horizons

The active participation of Chinese colleagues from Xi’an Jiaotong University gave the event particular significance. They expressed interest in combining the technological advantages of the two countries to achieve breakthrough scientific results.

Professor Long, head of the Institute of Mitochondrial Biomedicine, made specific proposals for the creation of a joint Russian-Chinese centre for mitochondrial metabolism and tissue microenvironment based at RUDN.

Participants unanimously noted the inspiring atmosphere and high level of the conference. This event will become a traditional platform bringing together global scientific teams to achieve breakthrough results at the intersection of fundamental morphology and clinical practice.