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RUDN University scientific and research innovations
RUDN University scientific and research innovations
  1. A process for the preparation of pyrrolo [2,1-a] isoquinoline derivatives (Borisova T.N., Varlamov A.V., Voskresensky L.G., Matveeva M.D.)
    The invention relates to the field of organic chemistry, namely to a process for the preparation of pyrrolo [2,1-a] isoquinoline derivatives 3-6, where in 3: R1 = OCH3, R2 = H, R3 = Cl, R4 = H; 4: R1 = OCH3, R2 = H, R3 = Cl, R4 = CH3; 5: R1 = R2 = R3 = OC2H5, R4 = H; 6: R1 = R2 = R3 = OC2H5, R4 = CH3, which comprises dissolving 6,7-dimethoxy-3,4-dihydro-1- (4-chlorobenzoyl) isoquinoline or 6,7-diethoxy-3,4-dihydro-1 - (3,4-diethoxybenzoyl) isoquinoline in acetonitrile and addition of 1,5-diphenyl-1-penten-4-yn-3-one or 1- (4-methylphenyl) -5-phenyl-1-penten-4-yn -3-one and 30 mole percent monovalent copper bromide and subjected to microwave irradiation (300 W) for 30 minutes at + 200 ° C, the residue obtained after the reaction ends and the solvent is removed is crystallized from ether. The technical result: a method for the preparation of pyrrolo [2,1-a] isoquinoline derivatives, which may have useful biological properties, has been developed.
  2. The method of purification from impurity proteins in preparations of molecular chaperones (Fedorov A.N., Yurkova M.S., Zenin V.A., Sadykhov E.G.)
    The method of purification from impurity proteins in preparations of molecular chaperones after their biosynthesis in bacterial cells. A method has been developed that allows to quickly and efficiently purify molecular chaperones after their expression in bacterial cells.
  3. Analysis of the efficiency of the virtualized mobile core network 5G (Abaev P.O., Tsarev A.S., Leon Atupanya M.K.)
    The program is used to simulate the operation of a virtualized core of a fifth-generation mobile network in the form of a multi-line queuing system with a dynamically changing number of serving devices. The program includes modules that calculate the characteristics of the system depending on the intensity of the input flow of applications, the total number of devices, the initial number of devices, the intensity of application maintenance and the intensity of the new device's rotation, the module that implements the analytical calculation of the probability distribution of the system, the module that implements the interface for saving the calculation results. The program contains support system module that allows to calculate the characteristics of the system for the ranges of input data. The program provides for finding the probability distribution of the system and its main probabilistic and temporal characteristics: the probability of system locking, the average queue length, the average waiting time for the start of the application maintenance.
  4. Device for reducing excess intraocular pressure (Kumar Vinod, Frolov Mikhail Alexandrovich, Dushina Galina, Shradkah Ahmad Saleh Soliman)
    A useful model refers to medicine, in particular to ophthalmology, and can be used in the surgical treatment of glaucoma of various genesis. The device for reducing excess intraocular pressure is made of stainless steel in the form of a tube and has a curvature equal to the circumference of a circle with a radius of 12.5 mm. Four burns through for liquid removal are made on the front wall of the device and located at an equal distance from each other and at a distance of 0.75 mm from the tail part of the device. The bottom wall of the device has a rectangular hole of 3.0 × 0.6 mm, located 1.0 mm from the tailing side of the device. The head part of the device is cut at an angle of 45 ° and has two lateral walls of triangular shape and a bottom wall made in the form of a tongue 1 mm long, 1 mm wide at the base to 0.3-0.4 mm at the tip of the tongue. Tip of the tongue has a curvature of radius 0.36 mm.
  5. Method for identification of chamomile flowers (Velikhanova Zaira Remikhanovna, Marakhova Anna Igorevna, Sorokina Alla Anatolievna, Stanishevsky Yaroslav Mikhailovich, Shvitko Boris Semenovich)
    The invention relates to pharmacological analysis, in particular to the establishment of the authenticity of chamomile pharmacy flowers.
    The identification of the authenticity of medicinal plant material is a particularly relevant issue in circumstances with its importation and the emergence of species related by morphology.
    • A method for identifying chamomile flowers that allows to distinguish the chamomile flowers from the foreign substance - flowers of a wild chamomile (scentless chamomile) by comparing the absorption spectra of solutions, characterized by analyzing solutions containing alcohol extracts of chamomile flowers and scentless chamomile flowers, a complexing agent and a buffer solution with pH , equal to 4-5, by a spectrophotometric method at a wavelength of 340 ± 2 nm.
    • A method for identifying flowers of chamomile, which allows qualitatively to distinguish chamomile flowers from a foreign substance - scentless chamomile flowers by comparing the absorption spectra of solutions according to item 1, characterized in that the complexing substance is aluminum chloride.
Main Publications View all
15 Nov 2017
RUDN University scientists publish results of their scientific researches in highly-recognized in whole world and indexed in international databases journals (Web of Science, Scopus ect.). That, of course, corresponds to the high status of the University and its international recognition. Publications of June-September 2017 ( In Journals of categories Q1-Q3)
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Student's Scientific Initiatives View all
03 Nov 2017
June 22 - 26, 2017 in Barnaul, Altai State University, took place the Summer Academy of the BRICS Youth Assembly, an international event that brought together representatives of different countries
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22 Oct
RUDN chemist creates catalyst to produce anti-mosquito substances

A chemist from RUDN University has developed a catalyst for the production of eugenol acetate, a substance that destroys the larvae of mosquitoes transmitting dangerous diseases, being a safe chemical for human health.

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22 Oct
RUDN soil scientists developed a new method for assessing soil fertility

RUDN soil scientists have revealed a direct correlation between the rate of soil formation of carbon dioxide, called CO2 emissions, and the content of microbial biomass in it. It is known that CO2 emission from soil is mainly conditioned by respiration of soil microorganisms and plant roots. The more CO2 soil emits, the more microbial biomass it usually contains. It was shown that CO2 emission by chernozem of different ecosystems (or different types of land use) correlates with the content of microbial biomass, and most closely with the rate of its microbial respiration. And the soil with good microbial properties has the “best quality”, is more fertile, provides the highest yield of crops and other plant biomass.

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22 Oct
RUDN University chemists proposed a way to reduce three times the temperature for the oxidation of alkanes

RUDN University chemists and their colleagues from the Russian Academy of Sciences have proposed new catalysts that allow to reduce the temperature of the oxidation reaction of alkanes three times — from 150 to 50 degrees. This significantly reduces the cost of synthesizing alcohols, aldehydes and other compounds needed, in particular, for the production of nylon and capron.

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