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RUDN University scientific and research innovations

RUDN University scientific and research innovations

  1. A process for the preparation of pyrrolo [2,1-a] isoquinoline derivatives (Borisova T.N., Varlamov A.V., Voskresensky L.G., Matveeva M.D.)
    The invention relates to the field of organic chemistry, namely to a process for the preparation of pyrrolo [2,1-a] isoquinoline derivatives 3-6, where in 3: R1 = OCH3, R2 = H, R3 = Cl, R4 = H; 4: R1 = OCH3, R2 = H, R3 = Cl, R4 = CH3; 5: R1 = R2 = R3 = OC2H5, R4 = H; 6: R1 = R2 = R3 = OC2H5, R4 = CH3, which comprises dissolving 6,7-dimethoxy-3,4-dihydro-1- (4-chlorobenzoyl) isoquinoline or 6,7-diethoxy-3,4-dihydro-1 - (3,4-diethoxybenzoyl) isoquinoline in acetonitrile and addition of 1,5-diphenyl-1-penten-4-yn-3-one or 1- (4-methylphenyl) -5-phenyl-1-penten-4-yn -3-one and 30 mole percent monovalent copper bromide and subjected to microwave irradiation (300 W) for 30 minutes at + 200 ° C, the residue obtained after the reaction ends and the solvent is removed is crystallized from ether. The technical result: a method for the preparation of pyrrolo [2,1-a] isoquinoline derivatives, which may have useful biological properties, has been developed.
  2. The method of purification from impurity proteins in preparations of molecular chaperones (Fedorov A.N., Yurkova M.S., Zenin V.A., Sadykhov E.G.)
    The method of purification from impurity proteins in preparations of molecular chaperones after their biosynthesis in bacterial cells. A method has been developed that allows to quickly and efficiently purify molecular chaperones after their expression in bacterial cells.
  3. Analysis of the efficiency of the virtualized mobile core network 5G (Abaev P.O., Tsarev A.S., Leon Atupanya M.K.)
    The program is used to simulate the operation of a virtualized core of a fifth-generation mobile network in the form of a multi-line queuing system with a dynamically changing number of serving devices. The program includes modules that calculate the characteristics of the system depending on the intensity of the input flow of applications, the total number of devices, the initial number of devices, the intensity of application maintenance and the intensity of the new device's rotation, the module that implements the analytical calculation of the probability distribution of the system, the module that implements the interface for saving the calculation results. The program contains support system module that allows to calculate the characteristics of the system for the ranges of input data. The program provides for finding the probability distribution of the system and its main probabilistic and temporal characteristics: the probability of system locking, the average queue length, the average waiting time for the start of the application maintenance.
  4. Device for reducing excess intraocular pressure (Kumar Vinod, Frolov Mikhail Alexandrovich, Dushina Galina, Shradkah Ahmad Saleh Soliman)
    A useful model refers to medicine, in particular to ophthalmology, and can be used in the surgical treatment of glaucoma of various genesis. The device for reducing excess intraocular pressure is made of stainless steel in the form of a tube and has a curvature equal to the circumference of a circle with a radius of 12.5 mm. Four burns through for liquid removal are made on the front wall of the device and located at an equal distance from each other and at a distance of 0.75 mm from the tail part of the device. The bottom wall of the device has a rectangular hole of 3.0 × 0.6 mm, located 1.0 mm from the tailing side of the device. The head part of the device is cut at an angle of 45 ° and has two lateral walls of triangular shape and a bottom wall made in the form of a tongue 1 mm long, 1 mm wide at the base to 0.3-0.4 mm at the tip of the tongue. Tip of the tongue has a curvature of radius 0.36 mm.
  5. Method for identification of chamomile flowers (Velikhanova Zaira Remikhanovna, Marakhova Anna Igorevna, Sorokina Alla Anatolievna, Stanishevsky Yaroslav Mikhailovich, Shvitko Boris Semenovich)
    The invention relates to pharmacological analysis, in particular to the establishment of the authenticity of chamomile pharmacy flowers.
    The identification of the authenticity of medicinal plant material is a particularly relevant issue in circumstances with its importation and the emergence of species related by morphology.
    • A method for identifying chamomile flowers that allows to distinguish the chamomile flowers from the foreign substance - flowers of a wild chamomile (scentless chamomile) by comparing the absorption spectra of solutions, characterized by analyzing solutions containing alcohol extracts of chamomile flowers and scentless chamomile flowers, a complexing agent and a buffer solution with pH , equal to 4-5, by a spectrophotometric method at a wavelength of 340 ± 2 nm.
    • A method for identifying flowers of chamomile, which allows qualitatively to distinguish chamomile flowers from a foreign substance - scentless chamomile flowers by comparing the absorption spectra of solutions according to item 1, characterized in that the complexing substance is aluminum chloride.
Main Publications View all
15 Nov 2017
RUDN University scientists publish results of their scientific researches in highly-recognized in whole world and indexed in international databases journals (Web of Science, Scopus ect.). That, of course, corresponds to the high status of the University and its international recognition. Publications of June-September 2017 ( In Journals of categories Q1-Q3)
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30 Jan 2018
The conference on international arbitration, where law students from European universities simulate court proceedings and alternately defend the interests of the respondent and the orator.
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30 Dec
Biologists from RUDN University discovered the secret of flaxseed oil with long shelf life

Biologists from RUDN University working together with their colleagues from the Institute of Molecular Biology of the Russian Academy of Sciences and the Institute of Flax studied the genes that determine the fatty acid composition in flaxseed oil and identified polymorphisms in six of them. The team also found out what gene variations could extend the shelf life of flaxseed oil. This data can be used to improve the genetic selection of new flax breeds. The results were published in the BMC Plant Biology journal.

74
30 Dec 2020
Researchers conducted a systematic review of articles that analyzed the effect of medicine remedies used to treat COVID-19 during pregnancy.

RUDN physician Anna Borisova, in collaboration with colleagues from Italy, used effective searches and classified 123 articles on this research topic. A literature review was conducted by searching databases of medical and biological publications: PubMed, the U.S. National Library of Medicine, and Embase (Elsevier), a biomedical database.

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30 Dec 2020
Each tree has a "cost". And smart technologies help to define it...

About Tree Talkers and soil structures, proper environmental management for sustainable urban development — in an interview with Elvira Davletyarov, Director of the Agrarian and Technological Institute of RUDN University.

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