RUDN University biologists received nanogold for medicine and agronomy
Gold nanoparticles can be used in delivery systems for anticancer drugs, as biosensors, in the creation of muscle tissue, and in other areas of modern medicine. In addition, gold nanoparticles also have an antifungal effect. This may be useful in agriculture to combat pathogenic fungi that attack plant crops. However, the antifungal properties of nanogold have still been largely unexplored. RUDN University biologists, together with colleagues from Iran, obtained gold nanoparticles from endophytic fungi, that is, fungi that live on plants and do not interfere with their vital functions. The resulting particles turned out to be an effective remedy against pathogenic fungi.
“Endophytic fungi are potential sources of bioactive substances that are used in medicine, agriculture, industry, and biology. Their derivatives exhibit antitumor, immunomodulatory, antituberculosis, antiviral and antidiabetic activity. Therefore, the study of endophytes living on various plants will make it possible to discover new useful compounds. At the same time, endophytes are easier to cultivate than other microorganisms,” Meysam Zargar, Candidate of Agricultural Sciences, Associate Professor of the Department of Agrobiotechnology of RUDN University.
RUDN biologists made endophytes living on the peach tree the source of nanogold. Biologists studied the effect of the resulting nanoparticles against the pathogenic fungus Rhizoctonia solani, which affects, for example, rice and potatoes.
Nanogold was able to destroy up to 93% of the pathogen. The experiment showed a direct dependence of efficiency on the number of nanoparticles: the maximum is achieved at a concentration of 80 micrograms per milliliter, and a concentration 8 times less can destroy 15% of the pathogen.
“Fungal-assisted biosynthesis opens the door to the development of sustainable and environmentally friendly gold nanoparticles with antibacterial properties. Their influence on crops is of growing interest and requires careful study. Our results provide a basis for the development of nanoparticle-based agents. They can provide a platform for future research, commercialization of products and hopefully help take a step towards sustainable agriculture,” Maysam Zargar.
The results were published in the journal Molecules.
RUDN summarized the results of the scientific competition "Project Start: work of the science club ". Students of the Faculty of Physics, Mathematics and Natural Sciences have created a project for a managed queuing system using a neural network to redistribute resources between 5G segments. How to increase flexibility, make the network fast and inexpensive and reach more users — tell Gebrial Ibram Esam Zekri ("Fundamental Computer Science and Information Technology", Master's degree, II course) and Ksenia Leontieva ("Applied Mathematics and Computer Science", Master's degree, I course).
The National Demographic Report, 2023 Demographic Well-Being of Russian Regions (hereinafter - the National Demographic Report) was prepared by the scientific team of the Institute of Demographic Studies of the Federal Research Center of the Russian Academy of Sciences, the Vologda Scientific Center of the Russian Academy of Sciences, Peoples' Friendship University of Russia, the Center for Family and Demography of the Academy of Sciences of the Republic of Tatarstan, as well as with the participation of leading scientists from the Republic of Bashkortostan, Stavropol Krai, Volgograd, Ivanovo, Kaliningrad, Nizhny Novgorod, Sverdlovsk Oblasts and Khanty-Mansi Autonomous Okrug–Yugra.
RUDN summarized the results of the scientific competition "Project Start: work of the science club ". Students of the Faculty of Physics, Mathematics and Natural Sciences have created a project for a managed queuing system using a neural network to redistribute resources between 5G segments. How to increase flexibility, make the network fast and inexpensive and reach more users — tell Gebrial Ibram Esam Zekri ("Fundamental Computer Science and Information Technology", Master's degree, II course) and Ksenia Leontieva ("Applied Mathematics and Computer Science", Master's degree, I course).
What is your first association with the word “laboratory”? Flasks and beakers? Microscopes and centrifuges? Yes, many of us would answer the same way.
The National Demographic Report, 2023 Demographic Well-Being of Russian Regions (hereinafter - the National Demographic Report) was prepared by the scientific team of the Institute of Demographic Studies of the Federal Research Center of the Russian Academy of Sciences, the Vologda Scientific Center of the Russian Academy of Sciences, Peoples' Friendship University of Russia, the Center for Family and Demography of the Academy of Sciences of the Republic of Tatarstan, as well as with the participation of leading scientists from the Republic of Bashkortostan, Stavropol Krai, Volgograd, Ivanovo, Kaliningrad, Nizhny Novgorod, Sverdlovsk Oblasts and Khanty-Mansi Autonomous Okrug–Yugra.