Lecture «Structure-based drug discovery: principles and applications in the main therapeutic areas»
Lecture «Structure-based drug discovery: principles and applications in the main therapeutic areas»
The event passed
8 Nov 2019
Location
Moscow, Ordzhonikidze st., 3, room 208
About the event

Since the first protein structures were determined through X-ray crystallography in the early 1960s, the knowledge of the three-dimensional structure of therapeutically relevant targets has informed and usefully supported drug discovery. Nowadays, structure-based drug design (SBDD), which has its roots in the modern tools of structural and computational biology, has become essential in assisting fast and cost-efficiently lead discovery and optimization.

The lecture will provide an overview of the principles, tools, applications and impact of structure-based drug design (SBDD) on the process of drug discovery. Some historical and recent case studies will be examined, with the aim of highlighting the value of SBDD in the design of high-quality chemical tools suitable for better understanding biology and disease pathology, informing target validation and ultimately accelerating drug discovery.

The event starts at 12:00

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